WebSulfasalazine is an exception and can cause a cross-reaction in patients with allergies to sulfonamide antimicrobials because it releases sulfapyridine (a cross-reactive arylamine sulfonamide) in contact with gut flora. Thus, use of sulfasalazine is contraindicated in patients with a significant allergy to sulfonamide antimicrobials. Webers identified allergies to sulfonamide an-tibiotics in 969 patients. Of this group, 96 patients (9.9%) had a subsequent reaction to a sulfonamide nonantibiotic, which in-cluded drugs …
Severe allergic reaction to hydrochlorothiazide mimicking
Web3 Oct 2024 · Common side effects of chlorthalidone may include: low blood pressure (feeling light-headed); kidney problems; dizziness; or. an electrolyte imbalance (such as low levels of potassium, sodium, or magnesium in your blood). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. WebThus, our results suggest that, if sulfonamide-based nonantibiotics were to be avoided in those with a prior sulfa allergy, they would also have to be avoided in those with a prior … cynthia czar michigan facebook
Sulfa Allergy: Drug List, Symptoms, Treatment, and …
WebHydrochlorothiazide (HCTZ) is a sulfonamide-containing drug with commonly reported adverse effects that include electrolyte abnormalities, orthostatic hypotension, hyperglycemia, and photosensitivity. A few reports have described rare but serious drug complications such as interstitial pneumonitis, … Web15 Sep 2024 · Thiazide diuretics inhibit the sodium-chloride symporter on the luminal surface (urine side) of the distal convoluted tubule, blocking sodium reabsorption and thereby promoting diuresis. ... Thiazides are sulfonamide derivatives, so use is cautioned in patients with a true sulfa-allergy given there may be cross-reactivity. In patients with a ... Web27 Feb 2024 · Metolazone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Metolazone is used to treat fluid retention ( edema) in people with congestive heart failure, or a kidney disorder such as nephrotic syndrome. Metolazone is also used to treat high blood pressure (hypertension). cynthia daelmans