WebJul 3, 2006 · Abstract. NUP98-HOXA9, the chimeric protein resulting from the t(7;11)(p15;p15) chromosomal translocation, is a prototype of several NUP98 fusions that occur in myelodysplastic syndromes and acute myeloid leukemia. We examined its effect on differentiation, proliferation, and gene expression in primary human CD34+ … WebIn t (2;11) (q31;p15), NUP98 fuses with HOXD11 or HOXD13.9 Transgenic mice …
NUP98 fusion oncoproteins interact with the APC/CC
Webphospho-Nup98 [cytosol] Stable Identifier. R-MMU-2990915 WebNUP98 Antibodies. Antibodies that detect NUP98 can be used in several scientific … heacham online
NUP98 gene fusions and hematopoietic malignancies: …
WebJan 21, 2024 · NUP98 fusion proteins cause leukemia via unknown molecular mechanisms. All NUP98 fusion proteins share an intrinsically disordered region (IDR) in the NUP98 N terminus, featuring repeats of ... WebJan 24, 2024 · NUP98 11p15 (R/G) AML Cytocell MLL/MLLT3 11q23 (R)/9p21 (G) Cytocell MLL/MLLT10 11q23 (R)/10p12.31 (G) Cytocell TP53/ATM 17p13.1 (R)/11q22.3 (G) CLL Cytocell CHROMOSOME 12 TEL/AML1 (ETV6/RUNX1) 12p13.2 (R)/ 21q22.12 (G) B-ALL Cytocell ETV6 12p13.2 (R/G ... WebApr 19, 2024 · In cells treated with FLT4.1, Nup98.1, and Nup98.2 siRNAs, the hemagglutinating activity decreased by 8 times. Conclusion: We identified a number of genes, such as FLT4, Nup98, and Nup205, whose expression can efficiently suppress viral reproduction when their expression is decreased. The original siRNA sequences were … heacham north beach car park