WebMay 28, 2024 · Ein weiterer, in kleinen unkontrollierten Therapiestudien beschriebener Ansatz ist die Gabe von Cyclophosphamid (CY) als metronomische Chemotherapie [ 3, 6, 12, 19 ]. CY ist ein Alkylans, das die Übertragung von Alkylgruppen in die DNA bewirkt und damit eine Vernetzungsreaktion zwischen den Strängen und Abbruch der Replikation … WebAug 17, 2024 · Cyclophosphamid bei Hunden. Cyclophosphamid ist ein auf Stickstoffsenf basierendes Medikament und hat 2 Hauptwirkungen: Es unterdrückt das Immunsystem und wird zur Behandlung von Hunden empfohlen, die eine abnorme Aktivität des Immunsystems aufweisen (z. B. Lupus oder andere Autoimmunerkrankungen). Beeinflusst die …
Cyclophosphamide Dosage Guide + Max Dose, Adjustments - Drugs.com
Cyclophosphamide (CP), also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and … See more Cyclophosphamide is used to treat cancers and autoimmune diseases. It is used to quickly control the disease. Due to its toxicity, it is replaced as soon as possible by less toxic drugs. Regular and frequent laboratory … See more Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) except for life-threatening circumstances in the mother. Additional relative contraindications to the use of … See more Oral cyclophosphamide is rapidly absorbed and then converted by mixed-function oxidase enzymes (cytochrome P450 system) … See more As reported by O. M. Colvin in his study of the development of cyclophosphamide and its clinical applications, Phosphoramide mustard, one of the principal toxic … See more Adverse drug reactions from cyclophosphamide are related to the cumulative medication dose and include chemotherapy-induced nausea and vomiting, bone marrow suppression, stomach ache, hemorrhagic cystitis, diarrhea, … See more The main effect of cyclophosphamide is due to its metabolite phosphoramide mustard. This metabolite is only formed in cells that have low levels of ALDH. Phosphoramide mustard forms DNA crosslinks both between and within DNA strands at See more The abbreviation CP is common, although abbreviating drug names is not best practice in medicine. See more WebJul 15, 2002 · High-dose cyclophosphamide, without stem cell rescue, has been used successfully to treat aplastic anemia and other autoimmune disorders. To determine the safety and efficacy of high-dose cyclophosphamide among patients with severe refractory autoimmune hemolytic anemia, we treated 9 patients with cyclophosphamide (50 mg · kg … chinese mental health journal的缩写
Thuốc Cyclophosphamide: Công dụng, chỉ định và lưu …
WebNov 28, 2024 · Alternative dose: 10 to 15 mg/kg IV every 7 to 10 days OR 3 to 5 mg/kg IV 2 times a week. Oral: 1 to 5 mg/kg/day (initial and maintenance dosing) Comments: Dosage should be individualized. The dosing recommendations provided here are guidelines. Many other regimens of IV and oral administration of this drug have been reported. WebOct 28, 2024 · Cyclophosphamide side effects. Cyclophosphamide injectable solution often causes nausea, vomiting, and loss of appetite. It can also cause dizziness, blurred … WebFeb 5, 2011 · Notice: Concentration information is not available for this spectrum and, therefore, molar absorptivity values cannot be derived. Additional Data grand piano replacement keys